Sertraline contains a combination of acetaminophen, butalbital, and caffeine. Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow. Sertraline is used to treat tension headaches that are caused by muscle contractions. Sertraline may also be used for purposes not listed in this medication guide.
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